교수소개

부교수

박준태
직책/직급
부교수
주전공
단백질공학
담당과목
단백질공학, 유전학, 후성유전체학, 바이오의약품학
전화번호
032-835-8841
이메일
joontae.park@inu.ac.kr
홈페이지
https://joon9657.wixsite.com/proteineng
학력

2009.05.21 Johns Hopkins Medicine  (박사)

2003.02.26 서울대학교  (석사)

2001.02.26 서울대학교  (학사)

경력

2016.01 ~ 2017.07 삼성바이오에피스 (전문연구원 (수석급))

2013.10 ~ 2015.12 삼성종합기술원 (전문연구원 (책임급))

2009.04 ~ 2013.09 Johns Hopkins University School of Medicine (Postdoctoral fellow)

연구실적
<논문> 

Establishment of a new promoter trapping vector using 2A peptide, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제29권(집) , 제3호 , PP.520~528 , 2024.06.01

Mucosal TLR5 activation controls healthspan and longevity, Nature Communications , 제15권(집) , 제1호 , PP.46~ , 2024.01.02

Polyporus ulleungus mycelia cultured in MEB medium produce metabolites with anticancer property, Journal of Cancer , 제15권(집) , 제2호 , PP.309~316 , 2024.01.01

Chemical screening identifies the anticancer properties of Polyporous tuberaster, Journal of Cancer , 제14권(집) , 제11호 , PP.2075~2084 , 2023.07.09

A novel hybrid promoter capable of continuously producing proteins in high yield, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , 제650권(집) , PP.103~108 , 2023.04.02

Targeting Mitochondrial Oxidative Stress as a Strategy to Treat Aging and Age-Related Diseases, Antioxidants , 제12권(집) , 제4호 , 2023.04.01

Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence, EXPERIMENTAL GERONTOLOGY , 제173권(집) , 2023.03.01

Chemical screening identifies the anticancer properties of Polyporous parvovarius, Journal of Cancer , 제14권(집) , 제1호 , PP.50~60 , 2023.01.01

Restoration of Lysosomal and Mitochondrial Function Through p38 Mitogen-Activated Protein Kinase Inhibition Ameliorates Senescence, REJUVENATION RESEARCH , 제25권(집) , 제6호 , PP.291~299 , 2022.12.01

Improvement of Tol2 Transposon System by Modification of Tol2 Transposase, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제27권(집) , 제6호 , PP.987~994 , 2022.12.01

A Ten-Minute Bioassay to Test Metal Toxicity with the Freshwater Flagellate Euglena agilis, Biology-Basel , 제11권(집) , 제11호 , PP.1618~ , 2022.11.05

Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3, Animal Cells and Systems , 제26권(집) , 제6호 , PP.275~282 , 2022.11.02

Co-inhibition of ATM and ROCK synergistically improves cell proliferation in replicative senescence by activating FOXM1 and E2F1, Communications Biology , 제5권(집) , 제1호 , 2022.07.14

Bacterial Artificial Chromosome-based Protein Expression Platform Using the Tol2 Transposon System, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제27권(집) , 제3호 , PP.344~352 , 2022.06.01

Improvement of Sleeping Beauty Transposon System Enabling Efficient and Stable Protein Production, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제27권(집) , 제3호 , PP.353~360 , 2022.06.01

The translational landscape as regulated by the RNA helicase DDX3, BMB Reports , 제55권(집) , 제3호 , PP.125~135 , 2022.03.31

Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence, Aging-US , 제14권(집) , 제2호 , PP.678~707 , 2022.01.17

Rapid and Efficient BAC Recombineering: Gain & Loss Screening System, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제26권(집) , 제6호 , PP.1023~1033 , 2021.12.01

Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence, Cells , 제10권(집) , 제11호 , 2021.11.03

Cre/Lox-based RMCE for Site-specific Integration in CHO Cells, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제26권(집) , 제5호 , PP.795~803 , 2021.10.01

Improvement of Tol2 Transposon System Enabling Efficient Protein Production in CHO Cells, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제26권(집) , 제5호 , PP.767~775 , 2021.10.01

Assessment of Various Toxicity Endpoints in Duckweed (Lemna minor) at the Physiological, Biochemical, and Molecular Levels as a Measure of Diuron Stress, Biology , 제10권(집) , 제7호 , PP.684~ , 2021.07.20

Disruption of nucleocytoplasmic trafficking as a cellular senescence driver, EXPERIMENTAL AND MOLECULAR MEDICINE , 제 53권(집) , 제6호 , PP.1092~1108 , 2021.06.29

Potential Treatment of Lysosomal Storage Disease Through Modulation of the Mitochondrial–Lysosomal Axis, Cells , 제10권(집) , 제2호 , PP.420~ , 2021.02.17

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition), Autophagy , 제17권(집) , 제1호 , PP.1~382 , 2021.02.08

Adiponectin Controls Nutrient Availability in Hypothalamic Astrocytes, International Journal of Molecular Sciences , 제22권(집) , 제4호 , PP.1~17 , 2021.02.04

Extracts of red seaweed, Pyropia yezoensis, inhibit melanogenesis but stimulate collagen synthesis, JOURNAL OF APPLIED PHYCOLOGY , 제33권(집) , 제1 호 , PP.653~662 , 2021.02.01

Identification of a novel senomorphic agent, avenanthramide C, via the suppression of the senescence-associated secretory phenotype, MECHANISMS OF AGEING AND DEVELOPMENT , 제192권(집) , PP.111355~ , 2020.12.01

ATM mediated-p53 signaling pathway forms a novel axis for senescence control, MITOCHONDRION , 제55권(집) , PP.54~63 , 2020.11.01

Identification of SYK inhibitor, R406 as a novel senolytic agent, Aging-US , 제12권(집) , 제9호 , PP.8221~8240 , 2020.05.15

Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence, EXPERIMENTAL GERONTOLOGY , 제126권(집) , 제2019호 , PP.110691~ , 2019.10.15

Zebrafish model of KRAS-initiated pancreatic endocrine tumor, Animal Cells and Systems , 제23권(집) , 제3호 , PP.209~218 , 2019.05.04

Alleviation of Senescence via ATM Inhibition in Accelerated Aging Models, MOLECULES AND CELLS , 제42권(집) , 제3호 , PP.210~217 , 2019.03.31

Functional evaluation of alternative splicing in the FAM190A gene, Genes & Genomics , 제41권(집) , 제2호 , PP.193~199 , 2019.02.01

Quantification of Autophagy During Senescence, Methods in Molecular Biology , 제1896권(집) , PP.149~157 , 2019.01.01

Zebrafish model of KRAS-initiated pancreatic cancer, Animal Cells and Systems , 제22권(집) , 제6호 , PP.353~359 , 2018.10.08

Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence, AGEING RESEARCH REVIEWS , 제47권(집) , PP.176~182 , 2018.08.21

A crucial role of ROCK for alleviation of senescence-associated phenotype, EXPERIMENTAL GERONTOLOGY , 제106권(집) , PP.8~15 , 2018.06.01

Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome, AGING CELL , 제16권(집) , 제3호 , PP.541~550 , 2017.06.16

Chemical screening identifies ATM as a target for alleviating senescence, Nature Chemical Biology , 제13권(집) , 제6호 , PP.616~623 , 2017.06.13

Ovarian cancer chemoresistance relies on the the stem cell reprogramming factor PBX1, CANCER RESEARCH , 제76권(집) , 제21호 , PP.6351~6361 , 2016.11.01

Method to purify and analyze heterogeneous senescent cell populations using a microfluidic filter with uniform fluidic profile, ANALYTICAL CHEMISTRY , 제87권(집) , 제19호 , PP.9584~9588 , 2015.10.06

Fate mapping of ptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish, DEVELOPMENTAL DYNAMICS , 제244권(집) , 제6호 , PP.724~735 , 2015.06.01

Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey, ONCOGENE , 제34권(집) , 제21호 , PP.2801~2806 , 2015.05.21

TAILOR: transgene activation and inactivation using lox and rox in zebrafish, PLoS One , 제8권(집) , 제12호 , PP.85218~ , 2013.12.31

Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish, DEVELOPMENTAL BIOLOGY , 제381권(집) , 제2호 , PP.471~481 , 2013.09.15

Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells, HEPATOLOGY , 제57권(집) , 제6호 , PP.2458~2468 , 2013.06.01

Notch3 overexpression is related to the recurrence of ovarian cancer and confers resistance to carboplatin, The American Journal of Pathology , 제177권(집) , 제3호 , PP.1087~1094 , 2010.09.01

Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer, CANCER RESEARCH , 제68권(집) , 제21호 , PP.8852~8860 , 2008.11.01

Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion, CANCER RESEARCH , 제68권(집) , 제14호 , PP.5716~5723 , 2008.07.15

Notch3 gene amplification in ovarian cancer, Cancer Research , 제66권(집) , 제12호 , PP.6312~6318 , 2006.06.15

Anaplasma phagocytophilum delay of neutrophil apoptosis through the p38 mitogen-activated protein kinase signal pathway, INFECTION AND IMMUNITY , 제73권(집) , 제12호 , PP.8209~8218 , 2005.12.01

Changes in profiles of major proteins in encysting Acanthamoeba castellanii, Animal Cells and Systems , 제6권(집) , 제4호 , PP.341~347 , 2002.11.20

<저서> 

캠벨 생명과학 12판, (주)바이오사이언스출판 , 2022.03.10

캠벨 생명과학의 이해 2판, (주)바이오사이언스출판 , 2022.03.10

캠벨 생명과학 포커스 3판, 바이오사이언스 , 2021.03.10

캠벨 생명과학 1 , 바이오사이언스출판 , 2019.05.30

Targeting Notch Signaling Pathway in Cancer Stem Cell. Cancer Stem Cells, Cambridge University Press , 2009.01.01